ISOLASI DAN IDENTIFIKASI SENYAWA METABOLIT SEKUNDER EKSTRAK ETIL ASETAT DAUN MANGKOKAN (NOTHOPANAX SCUTELLARIUM MERR)

Syafrinal Syafrinal

Abstract

This study aims to isolate and identify secondary metabolite compound contained in the extract ethyl acetate leaf of Mangkokan (Nothopanax scutellarium Merr. The methods used for isolation were maseration and column chromatography. The isolated compound is white powder with melting point  at 281-282 ° C. Test results with Liebermann-Buchard reagents forming a green ring showed positive steroids. The analysis by UV-Vis spectroscopy showed maximum absorption at 202 nm and analysis IR spectroscopy showed wave numbers (cm-1), are: 1021.25 (C-O), 1645.71 (C=C ), 2930.85 (C-H), 3364.66 (O-H)

Keywords

leaf of Mangkokan, Liebermann-Buchard, steroid

Full Text:

PDF

References

Achmad, S.A. 2004. Kimia Bahan Alam-Suatu pendekatan untuk memahami potensi keanekeragaman hayati dalam bioindustri. Prosiding pada Seminar Nasional IKAHIMKI 5 September 2004 di Surabaya

Montgomery, Duoglas C. 2016. Statistical Quality Control (7th edition). John Wiley &Sons Singapore Pte. Ltd.

Dalimartha, S. 1999. Atlas Tumbuhan Obat Indonesia, Jilid I. 86-89. 150-153. Trubus Agriwijaya. Jakarta.

Kitagawa, L. 1989. Progres in chemistry of medicinal plant in Asia. Proceedings of the Sixth Asian Symposium on Medicinal Plants and Spices. Bandung ITB University Press. 215.

Kohei Arai, et al. 2013. Identification of Ornamental Plant Functioned as Medicinal Plant Based on Redundant Discrete Wavelet Transformation. International Journal of Advanced Research in Artificial Intelligence. Vol. 2. No.3.

Kristati, A.N. 2008. Buku Ajar Fitokimia. Airlangga University Press. Surabaya.

Mai Efdi. et. al. 2007. The isolation of secondary metabolites and in vitro potent anti-cancer activity of clerodermic acid from Enicosanthum membranifolium. Elsevier, Bioorganic & Medicinal Chemistry. 15 (2007). 3667-3671.

Mamoru Koketsu, et.al. 2014. Phytochemical analysis and antileukemic activity of polyphenolic constituents of Toona sinensis. Elsevier. 501-1193.

Sofjan Assauri. 1998. Manajemen Operasi dan Produksi. Jakarta. LP FE UI.

Marliana, et. al. 2005. Skrining Fitokimia dan Analisis Kromatografi Lapis Tipis Komponen Kimia Labu Siam (Sechium edule Jacq. Swartz.) dalam Ekstrak Etanol. Biofarmasi. Vol. 3 (1). hal. 26-31.

Sandhya, et al. 2010. Evaluation of antiulcer activity of root and leaf extract of Polyscias balfouriana var.marginata. International Journal of Pharmaceutical and Clinical Research. 2(1). 192-195.

Sandhya, et al. 2010. Evaluation of Immunostimulant Activity of the Root and Leaf of Polyscias Balfouriana Marginata. International Journal of Pharmaceutical and Clinical Research. 2(2). 61-62.

Veblen, T.T. & Glenn, H.S. 2004. Comparison on forest structure and regeneration on bench and Stewart island, New Zealand. International Journal of Pharmaceutical and Clinical Research. 2(1). 192-195.

Refbacks

  • There are currently no refbacks.